NAD+: Research on Cellular Energy, Sirtuins, and Longevity
Share
Few molecules occupy as central a place in cellular metabolism as NAD+. Present in every living cell, this coenzyme has become a major focus of aging research over the past decade.
Overview
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme involved in hundreds of cellular oxidation-reduction reactions. It plays an essential role in mitochondrial ATP production and serves as a substrate for several families of regulatory enzymes.
Proposed mechanism of action
NAD+ is studied as a substrate for sirtuins and PARPs (poly-ADP-ribose polymerases), two enzyme families involved respectively in epigenetic regulation and DNA repair. Cellular NAD+ levels decline with age, which directs a large part of research toward mechanisms for restoring this cellular pool.
Scientific research focus
- Mitochondrial function and cellular energy production
- Aging biology
- Studies on sirtuin activation
- DNA repair models via PARPs
Purity & quality standards
CELLOVATE applies strict internal standards to ensure consistency and reliability:
- High-purity structure (≥99% HPLC)
- Independent third-party verification, batch by batch
- Batch-to-batch consistency
- Lyophilized form, nitrogen-sealed for stability
Storage & handling
NAD+ is supplied as a lyophilized powder. Once reconstituted, it should be stored between 2 and 8°C and used within the timeframe indicated on the supplied certificate of analysis.
Research use only
NAD+ is offered strictly as a research reagent for in-vitro and laboratory studies conducted by qualified professionals. It is not a drug, supplement, or cosmetic, and is not intended for human or animal use.
